17α-Estradiol Exerts Neuroprotective Effects on SK-N-SH Cells

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17a-Estradiol Exerts Neuroprotective Effects on SK-N-SH Cells

Estradiol (E2) has been shown to exert organizational, neurotrophic, and neuroprotective effects in the CNS. The present study assessed the specificity of the neuroprotective effects of estradiol for the potent 17b-isomer. SK-N-SH cells from a human neuroblastoma cell line, which we have shown to be estrogen-responsive, were cultured at low or high plating density. Then cells were exposed to 17...

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ژورنال

عنوان ژورنال: The Journal of Neuroscience

سال: 1997

ISSN: 0270-6474,1529-2401

DOI: 10.1523/jneurosci.17-02-00511.1997